International Journal of Research in Health Sciences,2017,5,3,44-48.
Published:July 2017
Type:Original Article
Authors:
Abstract:
5-{4'-[(4"-aryl)- 3"-cyno-2"-hydroxy- pyridine-6"-yl]-phenyl carbamido}-dibenz [b,f] azepines (4a -4k) derivatives are known to have pharmacological activities. The titled compounds (4a-4k) have been determined against various Gram +ve, Gram –ve bacteria and fungi and products are supported by IR, 1 H NMR, Mass spectra and elemental analysis. The titled compounds (4a-4k) have been synthesized by the condensation of 5-{4'-[(3"-aryl)-2"-Propene-1"-one]-Phenyl carbamido}-dibenz [b,f] azepines with ethyl cyano acetate and ammonium acetate.
Keywords:Antimicrobial, Cyano pyridine derivaties
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