Clinical Profile of Tubercular Lymphadenitis Amongst Indian population and Itís Response to Anti-Tubercular Therapy- A Retrospective Observational Study

Author : Munje Radha P, Gour Sanjay M, Paradkar Dipak, Sonawane Nilesh, Bhaskkar Vandana, Atram Jitesh

Introduction: India constitutes around one fifth of tuberculosis burden globally. Tuberculosis of lymph node constitutes 20-40% of extrapulmonary tuberculosis. It is difficult to determine end point of antituberculsis treatment as response is to be monitored clinically. We conducted study to monitor the response to Antitubercular Therapy (ATT) in patients with tubercular cervical lymphadenitis in our tertiary care centre. Methods: Retrospective observational study of records of 117 diagnosed cases of tubercular cervical lymphadenitis registered under DOTS at our tertiary care centre during 1st Aug 2014 to 31 Jan 2015 was done. Diagnosis was confirmed using fine needle aspiration cytology of lymph node. Results: Maximum patients were in the age group of 15-30 year (49.5%). 59% were Females & 41% were males. 32% of had associated dry cough, 11% had fever, weight loss in 13%, cough with expectoration in 4.27%. Extension of treatment was required in 64.50 % patients, while 35.50 %were cured with six months of DOTS therapy. Conclusion: We conclude that patient with TB lymphadenitis usually requires more than 6 months of treatment. HIV positivity & female gender were found to be statistically significant for extension of therapy (P=0.05 & P=0.001 respectively). Associated respiratory symptoms & LN AFB positivity were NOT found to be statistically significant for extension of therapy (P=0.58 & P=0.44 respectively).

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