Diagnostic Accuracy of Fine Needle Aspiration Cytology in Salivary Gland Neoplasms-2 Year Study

International Journal of Research in Health Sciences,2015,3,1,99-108.
Published:January 2015
Type:Original Article
Authors:
Author(s) affiliations:

Rama Raju Yadi1, Sandhya Rani Chetri2, EzhilArasi N3, Anunayi J4, Sreedhar V.V5

1-Associate Professor, 2-Senior Resident, 3-Professor & HOD, 4-Associate Professor, 5-Professor, Dept of Pathology, Osmania Medical College, Hyderabad, Telangana. INDIA.

Abstract:

Introduction: Mass in the salivary gland region often presents a diagnostic challenge. The present study is conducted to diagnose the benign and malignant neoplasms of the salivary glands based on cytomorphology and compare with histopathological diagnosis and to find out the sensitivity, specificity of FNAC of salivary gland lesions, with a note on age, sex, site distribution. Materials and Methods: FNAC was performed on salivary gland lesions from June 2011 to May 2013, department of pathology, at tertiary care centre. Smears were made fixed in alcohol, haematoxylin and eosin staining done. For these cases gross and histopathological examination done on partially resected or excised parotid gland neoplasms. Specimens were subjected for routine processing; slides prepared and stained with haemotoxylin and eosin. Total of 75 cases had cytological and histopathological correlation. Appropriate statistical analysis was done to analyse data. Results: Of 75 cases, majority (69.3%) of cases involved parotid gland followed by submandibular gland. Pleomorphic adenoma was commonest benign tumor; mucoepidermoid carcinoma commonest malignant tumor. Cystic lesions posed diagnostic difficulty resulting in false negative diagnosis in 4 cases, false positive diagnosis in 1 case. Interpretation a conclusion: Salivary gland neoplasms represent wide variety of benign and malignant neoplasms. Tumors most commonly involved parotid gland. Tumors with cystic component posed diagnostic difficulty on FNAC. The overall sensitivity, specificity and accuracy of FNAC in present study were 83.33%, 97.7%, and 92%, which are in concordance with other studies.

Pleomorphic adenoma- Cytosmears showing epithelial and mesenchymal components in fibrillarychondromyxoid background