To Study the Use of Nebulised 3% Hypertonic Saline in the Treatment of Viral Bronchiolitis in Hospitalized Children Upto Age of 18 Months

International Journal of Research in Health Sciences,2014,2,1,414-419.
Published:January 2014
Type:Original Article
Author(s) affiliations:

Abishek1, G Somaiah1*, B Srikanth1, S Venkateshwarlu2, A Hanumiah3, N S Vamsidhar

1-Department of Pediatrics, Mamata Medical College, Khammam, Andhra Pradesh, INDIA.

2-Department of Pulmonary Medicine, Mamata Medical College, Khammam, Andhra Pradesh, INDIA.

3-Department of General Medicine, Mamata Medical College, Khammam, A P, INDIA.


The purpose of study was to investigate the addition of frequently nebulised 3% hypertonic saline to the standard therapy of moderately ill infants hospitalized with typical viral bronchiolitis in a prospective randomized manner. Children attending the department of Paediatrics with moderately severe bronchiolitis during June 2011 - May 2013.82children between1 month to 18 months of age. Baseline demographic data collected at study entry included inclusion and exclusion criteria, age, gender, duration of illness before study, concomitant medications and other illnesses. Data was collected by taking interview of parents regarding complaints. Observation of findings and investigations were recorded. Clinical history and examination were done as per the case proforma. Assessment of patients with RDAI score and SaO2 readings by pulse oximeter were done within 12 hrs of admission (study entry) and at least two times daily till patient attained protocol defined discharge criterion. Addition of 3 % hypertonic saline to standard therapy in sample of children aged upto 18 months admitted as moderately ill viral bronchiolitis demonstrated efficacy in terms of reduction in length of stay compared to control group consisting of standard therapy only ( p < 0.05), without increasing cost of treatment or significant side effects. The use of nebulised 3% hypertonic saline in addition to the standard therapy (i.e. nebulised salbutamol along with supportive therapy) in treating viral bronchiolitis in moderately ill hospitalized children upto age of 18 months reduces length of stay in hospital by half a day compared to those getting standard therapy alone

Respiratory Distress Assessment Instrument (RDAI) [13]